I honestly don't know, a lot depends on who they're going to kill in the second half of the story. FE Mitsuki is the most likely one for me, also if Kishi/Ikemoto has the guts, then I'd assume that Boruto will end up in the grave too (the shadow hokage role or whatever).
+ I doubt that there will be many couples in the end. If Inojin and Hima survive, then IH will be canon, no doubt, same goes for Bsa, prob Mitsuchou (but I wouldn't bet on Mitsuki's life) and Iwabe/Wasabi.
There is also a fanservice option that I really hope won't happen, but if it does so kwsu and shika/yodo